Thyroid Follicular Adenoma with Accumulation of Collagen Type IV in a Common Marmoset (Callithrix jacchus)
| Autor: | Yumi Wako, Minoru Tsuchitani, Masao Hamamura, Kazufumi Kawasako, Takeshi Kanno, Takuya Doi |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adenoma
Collagen Type IV Male endocrine system medicine.medical_specialty Pathology Thyroid Gland Basolateral cytoplasm Pathology and Forensic Medicine biology.animal Internal medicine Eosinophilic medicine Animals Endocrine system Thyroid Neoplasms Basement membrane General Veterinary biology Thyroid Marmoset Callithrix biology.organism_classification Endocrinology medicine.anatomical_structure Immunohistochemistry |
| Zdroj: | Journal of Comparative Pathology. 150:71-74 |
| ISSN: | 0021-9975 |
| DOI: | 10.1016/j.jcpa.2013.07.001 |
| Popis: | A thyroid tumour was identified in a 10-year-old male common marmoset (Callithrix jacchus). The tumour was encapsulated by fibrous connective tissue and compressed the adjacent normal thyroid. The tumour was composed of variably sized and irregularly shaped thyroid follicles lined by a single layer of columnar epithelial cells. Eosinophilic material at the base of the neoplastic cells stained black with periodic acid-methenamine silver and red with periodic acid-Schiff. Immunohistochemistry confirmed that this eosinophilic material was collagen type IV. Ultrastructurally, highly dense and amorphous material was observed at the base of the neoplastic cells. Small vesicles in the basolateral cytoplasm of the neoplastic cells contained similar material to that at the base of the cells. The tumour was diagnosed as a thyroid follicular adenoma with accumulation of collagen type IV. This is the first description of an endocrine tumour with accumulation of collagen type IV in animals. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect