Testosterone replacement therapy and polycythemia in HIV-infected patients
| Autor: | Marshall J. Glesby, Charles Kyriakos Vorkas, Carlos M. Vaamonde |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Hormone Replacement Therapy Immunology Polycythemia Administration Cutaneous Injections Intramuscular Risk Assessment Article Hemoglobins Elevated hemoglobin Internal medicine HIV Seropositivity Odds Ratio medicine Humans Immunology and Allergy Hiv infected patients Testosterone Testosterone replacement Retrospective Studies business.industry Hypogonadism Odds ratio Middle Aged Infectious Diseases Endocrinology Case-Control Studies Androgens business |
| Zdroj: | AIDS. 26:243-245 |
| ISSN: | 0269-9370 |
| DOI: | 10.1097/qad.0b013e32834db446 |
| Popis: | We conducted a case-control study to assess testosterone use as a primary risk factor for polycythemia in 21 HIV-infected men. Any testosterone use within 2 months of first elevated hemoglobin was associated with polycythemia (matched odds ratio 6.55; 95% confidence interval 1.83-23.4; P = 0.004) and intramuscular administration demonstrated a stronger association than topical use. No adverse cardiovascular or thrombotic events were observed. HIV-infected patients taking testosterone should undergo routine hematologic monitoring with adjustment of therapy when appropriate. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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