Removal of unilateral endometriomas is associated with immediate and sustained reduction in ovarian reserve

Autor: Ramazan Mercan, Kayhan Yakin, Bulent Urman, Cengiz Alatas, Senai Aksoy, Ozgur Oktem, Baris Ata, Ebru Alper
Přispěvatelé: Uludağ Üniversitesi/Tıp Fakültesi/Kadın Hastalıkları ve Doğum Anabilim Dalı., Ata, Barış
Rok vydání: 2013
Předmět:
Anti-Mullerian Hormone
Antral follicle count
medicine.medical_treatment
Primary Ovarian Insufficiency
Severity of Illness Index
In-vitro fertilization
Postoperative Complications
Ovarian Follicle
Observational study
Cyst
Obstetrics & gynecology
Dienogest
Ovarian Reserve
Elagolix
Ultrasonography
Quantitative rather
Cysts
Obstetrics and Gynecology
Cyst stripping
Ovary follicle
Middle Aged
Implantation
Ovarian Cysts
Damage
Follicular Phase
Female
Human
Adult
endocrine system
medicine.medical_specialty
Clinical article
Endometriosis
Reproductive biology
Laparoscopic cystectomy
Excision
Endometrium tumor
Insights
Article
Young Adult
medicine
Humans
Endometrioma
Ovarian reserve
Reduction (orthopedic surgery)
Managemen
business.industry
Ovary
Cauterization
Capsule
Antral follicle
medicine.disease
Surgery
Reproductive Medicine
Concentration (parameters)
Laparoscopy
business
Organ Sparing Treatments
Biomarkers
Developmental Biology
Hormone
Muellerian inhibiting factor
Follow-Up Studies
Zdroj: Reproductive biomedicine online. 27(2)
ISSN: 1472-6491
Popis: Endometrioma surgery by stripping the cyst capsule has been associated with a reduction in ovarian reserve. It is still not clear whether the inflicted damage is immediate, sustained over time or associated with the use of electrocautery, nor which marker is more accurately reflects the post-operative reduction in ovarian reserve. This observational study assessed the damage inflicted by endometrioma removal with anti-Mullerian hormone (AMH) concentration and antral follicle count (AFC) pre and post-operatively. Twenty-five women with unilateral endometrioma underwent laparoscopic stripping of the endometrioma cyst capsule. There was a significant decrease both in AMH concentration (24%) and in AFC (11%) 1 month following surgery ( P Endometrioma surgery by stripping the cyst capsule has been associated with a reduction in ovarian reserve. It is still not clear whether the inflicted damage is immediate, sustained over time or associated with the use of electrocautery, nor which marker more accurately reflects the post-operative reduction in ovarian reserve. In this observative study, we assessed the damage inflicted by endometrioma removal with anti-Mullerian hormone (AMH) and antral follicle count (AFC) pre- and post-operatively. Twenty-five women underwent laparoscopic stripping of the endometrioma cyst capsule. There was a 24% decrease in AMH concentration and an 11% decrease in AFC compared with the preoperative values 1month following surgery. The values did not change 6months after surgery over those recorded at 1month post-operatively (24 and 15% less than preoperative values. Primordial follicles embedded adjacent to the cyst capsule were found in 61.5% of the specimens. Endometrioma surgery by stripping of the cyst capsule is associated with a significant reduction in ovarian reserve. The reduction is immediate and sustained over time. AMH appears to be a better indicator for post-operative quantification of the ovarian reserve.
Databáze: OpenAIRE
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