Role of drug exposure in aphthous ulcers: a case–control study

Autor: Agnès Sparsa, P. Bernard, V Le Brun, S. Reix, Jean-Marie Bonnetblanc, Bouyssou-Gauthier Ml, P. De Vencay, Christophe Bedane, Serge Boulinguez, C. Debrock
Rok vydání: 2000
Předmět:
Zdroj: British Journal of Dermatology. 143:1261-1265
ISSN: 1365-2133
0007-0963
DOI: 10.1046/j.1365-2133.2000.03898.x
Popis: Background Drug-induced aphthous ulcers have been the subject of several isolated and heterogeneous case reports for the last three decades. Objectives To perform a case–control study to evaluate the risks linked to drug exposure in aphthous ulcers. Methods Eighty patients with typical clinical patterns of aphthous ulcers and 152 control patients who had had consultations for skin tumours were studied. A standardized questionnaire, concerning clinical features, life-style and medications taken during the last month, was completed for each patient. Results Case patients had a much higher intake of medications than control patients, respectively, 5·1 and 2·8 medications per patient (P
Databáze: OpenAIRE