The role of hydrogen peroxide in hip arthroplasty: A narrative review
| Autor: | Caitlyn Tran, Azeem Thahir, Shaan Patel, Milind Girish, Matija Krkovic, Jiang An Lim, Andrew Kailin Zhou |
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| Přispěvatelé: | Zhou, Andrew Kailin [0000-0001-6656-8123], Girish, Milind [0000-0003-0599-5265], An Lim, Jiang [0000-0003-1610-7956], Tran, Caitlyn [0000-0002-1798-8938], Patel, Shaan [0000-0003-2657-8874], Apollo - University of Cambridge Repository |
| Rok vydání: | 2021 |
| Předmět: |
musculoskeletal diseases
medicine.medical_specialty medicine.medical_treatment Arthroplasty Replacement Hip Embolism Periprosthetic Arthroplasty 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine medicine Humans Hydrogen peroxide Irrigation Reduction (orthopedic surgery) Prosthesis loosening 030222 orthopedics business.industry Hydrogen Peroxide Surgery Prosthesis Failure Oxygen Medical–Surgical Nursing Hip arthroplasty Anesthesiology and Pain Medicine Orthopedics chemistry Narrative review Aseptic processing Hip Prosthesis business 030217 neurology & neurosurgery |
| Zdroj: | Journal of perioperative practice. 32(7-8) |
| ISSN: | 2515-7949 |
| Popis: | Hydrogen peroxide has become more commonly used in hip arthroplasties due to high risk of periprosthetic infections. Its purported roles include irrigation, haemostasis, reduction of aseptic loosening and attachment of antibiotics. However, current literature does not provide conclusive evidence on the efficacy of hydrogen peroxide in preventing aseptic loosening, with some controversy around whether it in fact contributes to aseptic loosening. The complications of hydrogen peroxide across medicine are well distinguished; however, the risks within orthopaedic surgery and hip arthroplasties are not well known. Beyond cytotoxicity, the most dangerous reported risk associated with hydrogen peroxide in hip arthroplasties was an oxygen embolism in an unvented femoral canal and acrylic bone cement, consequentially leading to cardiac arrest. However, it may be inappropriate to solely attribute the oxygen embolism to the use of hydrogen peroxide and thus if used appropriately, hydrogen peroxide may have a justifiable role in hip arthroplasty surgery. In this narrative review, we present the current uses of hydrogen peroxide while evaluating its associated risks. We have summarised the key indications and aggregated recommendations to provide guidelines for the use of hydrogen peroxide in hip arthroplasty. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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