SPECT myocardial perfusion imaging identifies myocardial ischemia in patients with a history of COVID-19 without coronary artery disease

Autor: Emrah Erdoğan, Muhammed Süleymanoğlu, Murat Çap, Metin Okşul, İsmail Tatlı, Abdurrahman Akyüz, Cihan Gündoğan, Önder Bilge, Ibrahim Halil Tanboga, Mesut Oktay, Cansu Öztürk, Ercan Taştan, Ali Karagöz, Ferat Kepenek, Cengiz Burak, Ferhat Işık
Rok vydání: 2021
Předmět:
Zdroj: The International Journal of Cardiovascular Imaging
ISSN: 1573-0743
1569-5794
Popis: We aimed to examine the effect of a history of COVID-19 on myocardial ischemia in single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) in patients who presented with shortness of breath and/or chest pain after recovery. For this single-center retrospective study, patients who presented at cardiology outpatient clinics and had SPECT-MPI were screened. A total of 1888 patients were included in the study, 340 of whom had a history of COVID-19. 64 patients with > 50% stenosis on coronary angiography were excluded from the study. The primary outcome of the study was abnormal MPI. In the study population, the median age was 56 (49-64 IQR) years, and 1127 (65%) of the patients were female. Abnormal MPI was detected in 77 patients (23%) in the COVID-19 group and in 244 patients (16%) in the non-COVID-19 group. After adjustment was performed for clinical predictors using Bayesian logistic regression, an important association was found between the presence of a confirmed prior COVID-19 infection and abnormal MPI (posterior median odds ratio, 1.70 [95% CrI, 1.20-2.40], risk difference, 9.6% [95% CrI, 1.8%, 19.7%]). In SPECT-MPI, ischemia rates were observed to be higher in COVID-19 group and it was found that a confirmed prior COVID-19 might predict of abnormal MPI.
Databáze: OpenAIRE
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