WITHDRAWN: Can quantitative RT-PCR for SARS-coV-2 help in better management of patients and control of coronavirus disease 2019 pandemic

Autor: Ashok Rattan, Hafiz Imtiaz Ahmad
Jazyk: angličtina
Rok vydání: 2020
Předmět:
0301 basic medicine
lcsh:QR1-502
Review Article
Genome
lcsh:Microbiology
law.invention
COVID-19 Testing
0302 clinical medicine
Immunology and Microbiology (miscellaneous)
law
Pandemic
Immunology and Allergy
Medicine
030212 general & internal medicine
Polymerase chain reaction
biology
Reverse Transcriptase Polymerase Chain Reaction
Viral Load
sars-cov-2
Infectious Diseases
Real-time polymerase chain reaction
RNA
Viral
Coronavirus Infections
Viral load
Microbiology (medical)
medicine.medical_specialty
COVID-19 Vaccines
Isolation (health care)
Pneumonia
Viral
030106 microbiology
Immunology
Genome
Viral
Real-Time Polymerase Chain Reaction
Microbiology
Article
cycle threshold
Betacoronavirus
coronavirus disease 2019
03 medical and health sciences
Humans
patient management
Pandemics
quantitative rt-pcr
General Immunology and Microbiology
Clinical Laboratory Techniques
business.industry
Public health
COVID-19
RNA virus
biology.organism_classification
Virology
business
Zdroj: Indian Journal of Medical Microbiology
Indian Journal of Medical Microbiology, Vol 38, Iss 3, Pp 284-287 (2020)
ISSN: 0255-0857
DOI: 10.1016/j.ijmmb.2020.10.016
Popis: The emergence of SARS-CoV-2, the causative agent of coronavirus disease 2019 (COVID-19), represents a public health emergency of unprecedented proportion. The global containment efforts have been focused on testing, tracing of contacts and treatment (isolation) of those found COVID-19 positive. Since the whole genome sequences of a number of strains of this novel RNA virus were available in the public domain by early January 2020, a number of real-time polymerase chain reaction (RT-PCR) protocols were designed and used for diagnosis of this infection. Most RT-PCRs are designed for qualitative COVID-19 reporting (SARS-CoV-2 detected or not detected), but have been used for semi-quantitative estimation of viral load based on cycle threshold value. Our manuscript discusses the utility of quantitative PCR testing for COVID-19 and its patient management benefits.
Databáze: OpenAIRE
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