| Autor: |
Ben C. Giglio, Matt J. Keough, Rene P.F. Kanters, Matthew B. Coppock, Melissa D. Sartin, Kristin L. Smith, James A. Sikorski, Timothy M. Smith, Edith J. Banner, Daniel C. Fisher, John T. Gupton, Jonathan E. Hempel, Anastasia Kharlamova, Raymond N. Dominey |
| Jazyk: |
angličtina |
| Rok vydání: |
2008 |
| Předmět: |
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| Popis: |
Studies directed at the synthesis of polycitone and storniamide natural products via vinylogous iminium salts and microwave accelerated Vilsmeier-Haack formylations are described. The successful strategy relies on the formation of a 2,4-disubstituted pyrrole or a 2,3,4-trisubstituted pyrrole from a vinamidinium salt or vinamidinium salt derivative followed by formylation at the 5-position of the pyrrole. Subsequent transformations of the selectively formylated pyrroles lead to efficient and regiocontrolled relay syntheses of the respective pyrrole containing natural products. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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