Antimicrobial activity and essential oils of Curcuma aeruginosa, Curcuma mangga, and Zingiber cassumunar from Malaysia
| Autor: | Tg Siti Amirah Tg Kamazeri, Muhammad Taher, Deny Susanti, Haitham Qaralleh, Othman Abd. Samah |
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| Jazyk: | angličtina |
| Předmět: |
Microbial Sensitivity Tests
Essential oil Curcuma mangga law.invention Zingiber cassumunar Curcuma Anti-Infective Agents law Zingiberaceae Botany Oils Volatile Plant Oils Curcuma aeruginosa Medicine(all) biology Traditional medicine Bacteria Fungi Malaysia General Medicine biology.organism_classification Antimicrobial Gas chromatography-mass spectrometry Phytotherapy |
| Zdroj: | Asian Pacific Journal of Tropical Medicine. (3):202-209 |
| ISSN: | 1995-7645 |
| DOI: | 10.1016/S1995-7645(12)60025-X |
| Popis: | ObjectiveTo analyze the chemical composition of the essential oils of Curcuma aeruginosa (C. aeruginosa), Curcuma mangga (C. mangga), and Zingiber cassumunar (Z. cassumunar), and study their antimicrobial activity.MethodsEssential oils obtained by steam distillation were analyzed by gas chromatography-mass spectrometry (GC-MS). The antimicrobial activity of the essential oils was evaluated against four bacteria: Bacillus cereus (B. cereus), Staphylococcus aureus (S. aureus), Escherichia coli (E. coli), and Pseudomonas aeruginosa (P. aeruginosa); and two fungi: Candida albicans (C. albicans) and Cyptococcus neoformans (C. neoformans), using disc-diffusion and broth microdilution methods.ResultsCycloisolongifolene, 8,9-dehydro formyl (35.29%) and dihydrocostunolide (22.51%) were the major compounds in C. aeruginosa oil; whereas caryophyllene oxide (18.71%) and caryophyllene (12.69%) were the major compounds in C. mangga oil; and 2,6,9,9-tetramethyl-2,6,10-cycloundecatrien-1-one (60.77%) and α-caryophyllene (23.92%) were abundant in Z. cassumunar oil. The essential oils displayed varying degrees of antimicrobial activity against all tested microorganisms. C. mangga oil had the highest and most broad-spectrum activity by inhibiting all microorganisms tested, with C. neoformans being the most sensitive microorganism by having the lowest minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) values of 0.1μL/mL. C. aeruginosa oil showed mild antimicrobial activity, whereas Z. cassumunar had very low or weak activity against the tested microorganisms.ConclusionsThe preliminary results suggest promising antimicrobial properties of C. mangga and C. aeruginosa, which may be useful for food preservation, pharmaceutical treatment and natural therapies. |
| Databáze: | OpenAIRE |
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