Thyroid fine‐needle aspiration cytology: Performance data of neoplastic and malignant cases as identified from 1558 responses in the ASCP Non‐GYN Assessment program thyroid fine‐needle performance data

Autor: Indra Balachandran, Perkins Mukunyadzi, Umesh Kapur, Ajay Shah, Amy Wendel Spiczka, Paula LaPolice, Adebowale J. Adeniran, Husain Saleh, Stan G. Eilers, Amberly L. Nunez, Jennifer J. Clark, Larry Lemon
Rok vydání: 2014
Předmět:
Male
Cancer Research
Databases
Factual
medicine.medical_treatment
medicine.disease_cause
follicular
Adenocarcinoma
Follicular
thyroid cancer
Adenoma
Oxyphilic
Thyroid Nodule
Thyroid cancer
Societies
Medical
thyroid carcinoma
papillary
Thyroid
Immunohistochemistry
medicine.anatomical_structure
Oncology
Thyroid Cancer
Papillary
Thyroidectomy
Female
thyroid carcinoma
anaplastic
Radiology
Thyroid nodules
endocrine system
medicine.medical_specialty
Cytodiagnosis
Biopsy
Fine-Needle
Risk Assessment
Diagnosis
Differential
Thyroid carcinoma
medicine
Carcinoma
Humans
Neoplasm Invasiveness
Thyroid Neoplasms
thyroid carcinoma
follicular
Hurthle cell thyroid neoplasia
Thyroid neoplasm
thyroid cancer
Hurthle cell
Neoplasm Staging
business.industry
thyroid carcinoma
medullary
General surgery
Original Articles
medicine.disease
Carcinoma
Papillary
Carcinoma
Neuroendocrine
Cytopathology
business
follicular thyroid neoplasm
Zdroj: Cancer Cytopathology
ISSN: 1934-6638
1934-662X
DOI: 10.1002/cncy.21440
Popis: BACKGROUND: Fine-needle aspiration of the thyroid is a common procedure, with an established role in reducing unnecessary thyroid surgery and identifying neoplasms and malignancies. METHODS: The study evaluated 1558 responses in the American Society for Clinical Pathology (ASCP) Non-GYN Assessment program of aspirates of thyroid neoplasms and malignancies and placed them into the following groups: group A (target or correct interpretation), group B (incorrect interpretation as a benign thyroid nodule), group C (incorrect interpretation malignant aspirate as thyroid neoplasm), and group D (malignant diagnosis with incorrect interpretation). In clinical practice, responses in groups A, C, and D would lead to surgical excision, whereas responses in group B would not. RESULTS: Of a total of 1558 responses, 78.5% of the responses were in group A, 8.5% in group B, 3.75% in group C, and 9.25% in group D. By individual diagnosis, the group rates were 86.5%, 0%, 11%, and 2.5% for anaplastic thyroid carcinoma; 83%, 5.5%, 4.25%, and 7.25% for papillary thyroid carcinoma; 79%, 7%, 6%, and 8% for medullary thyroid carcinoma; 83.5% 6.75%, 0%, and 9.75% for H€ urthle cell neoplasm; and 61%, 22%, 0%, and 17% for follicular neoplasm in groups A, B, C, and D respectively. CONCLUSIONS: Fineneedle aspiration was effective in diagnosing thyroid neoplasms and malignancies and in separating thyroid nodules into surgical and nonsurgical categories. Data from a large group of cytology professionals showed good performance; however, there is room for improvement, especially in making specific diagnoses. In particular, follicular neoplasm and follicular variant of papillary thyroid carcinoma were challenging diagnoses for participants. Cancer (Cancer Cytopathol) 2014;000:000-000. V C 2014 The Authors. Cancer Cytopathology published by Wiley Periodicals, Inc. on behalf of American Cancer Society. This is an open access article under the terms of the Creative Commons Attribution NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
Databáze: OpenAIRE
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