Contribution of Candida albicans ALS1 to the Pathogenesis of Experimental Oropharyngeal Candidiasis
| Autor: | Yoko Kamai, Mikie Kubota, Yasuki Kamai, Scott G. Filler, Tsunemichi Hosokawa, Takashi Fukuoka |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Immunology
In Vitro Techniques Microbiology Oropharyngeal Candidiasis Fungal Proteins Gene product Pathogenesis Mice Tongue Candidiasis Oral Candida albicans Cell Adhesion medicine Animals Oral mucosa Mycosis Fungal protein Virulence biology biology.organism_classification medicine.disease Bacterial adhesin Infectious Diseases medicine.anatomical_structure Mutation Parasitology Fungal and Parasitic Infections |
| Zdroj: | Infection and Immunity. 70:5256-5258 |
| ISSN: | 1098-5522 0019-9567 |
| DOI: | 10.1128/iai.70.9.5256-5258.2002 |
| Popis: | We investigated the contribution of Candida albicans ALS1 , which encodes a candidal adhesin, to the pathogenesis of experimental murine oropharyngeal candidiasis. Our results indicate that the ALS1 gene product is important for the adherence of the organism to the oral mucosa during the early stage of the infection. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|