Moderate-to-severe Endoscopic Inflammation is Frequent After Clinical Remission in Pediatric Ulcerative Colitis
| Autor: | Dror Weiner, Michal Yaakov, Lee Abramas, Chen Sarbagili-Shabat, Joram Wardi, Arie Levine |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Moderate to severe medicine.medical_specialty Pediatric ulcerative colitis Inflammation Disease Activity index Severity of Illness Index 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Internal medicine medicine Humans Prospective Studies Intestinal Mucosa Risk factor Child Retrospective Studies medicine.diagnostic_test business.industry Remission Induction Gastroenterology Sigmoidoscopy Colonoscopy Endoscopy Pediatrics Perinatology and Child Health Colitis Ulcerative 030211 gastroenterology & hepatology medicine.symptom business |
| Zdroj: | Journal of Pediatric Gastroenterology & Nutrition. 72:569-573 |
| ISSN: | 1536-4801 0277-2116 |
| Popis: | OBJECTIVES Pediatric ulcerative colitis (UC) is characterized by low sustained remission rates and frequent extension of disease even if clinical remission is obtained with therapy. Moderate-to-severe endoscopic activity is a risk factor for relapse while prospective evidence regarding early mucosal healing or persistence of inflammation after remission in children is not available. Our aim was to evaluate if significant inflammation is common after clinical remission and could explain the high relapse rate in pediatric UC. METHODS Pediatric UC patients with clinical remission, defined as pediatric UC activity index (PUCAI) scores |
| Databáze: | OpenAIRE |
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