Two new xyloketals from the endophytic fungus Endomelanconiopsis endophytica derived from medicinal plant Ficus hirta
| Autor: | Yuchan Chen, Hongxin Liu, Fa-Liang Liang, Weimin Zhang, Zhang-Hua Sun, Hao-Hua Li |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Liquid culture Pharmaceutical Science Tumor cells Biology 01 natural sciences Analytical Chemistry 03 medical and health sciences chemistry.chemical_compound Ascomycota Drug Discovery Botany Humans Pyrans Pharmacology Folk medicine Plants Medicinal Natural product Molecular Structure 010405 organic chemistry Organic Chemistry Hep G2 Cells General Medicine Endophytic fungus Ficus 0104 chemical sciences 030104 developmental biology Complementary and alternative medicine chemistry Ficus hirta Molecular Medicine Drug Screening Assays Antitumor Endomelanconiopsis endophytica |
| Zdroj: | Journal of Asian Natural Products Research. 18:1036-1041 |
| ISSN: | 1477-2213 1028-6020 |
| DOI: | 10.1080/10286020.2016.1188084 |
| Popis: | Chemical examination of the liquid culture of Endomelanconiopsis endophytica A326 isolated from the Chinese folk medicine Ficus hirta resulted in the isolation of two new xyloketals named xyloketals K and L (1–2) and three known analogs (3–5) including a new natural product (5). Their structures were determined on the basis of extensive spectroscopic analysis. All compounds were evaluated for their cytotoxic activities against the SF-268, MCF-7, NCI-H460, and HepG-2 tumor cell lines. Nonetheless, no significant activity was observed. |
| Databáze: | OpenAIRE |
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