Cefotaxime-resistant E. coli in dairy and beef cattle farms—Joint analyses of two cross-sectional investigations in Germany
| Autor: | Katja Hille, Annemarie Käsbohrer, Anika Friese, Maria Hartmann, Ute Messelhäusser, Stefan Hörmansdorfer, Johanna Hering, Christiane von Münchhausen, R. Mansfeld, Lothar Kreienbrock, Bettina Schneider, Uwe Roesler, Inga Ruddat, Annette Schmid |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Veterinary medicine Farms Cefotaxime medicine.drug_class media_common.quotation_subject 030106 microbiology Cephalosporin Population Antibiotics Cattle Diseases Beef cattle Biology 03 medical and health sciences Animal science Food Animals Hygiene Germany Drug Resistance Bacterial Escherichia coli Prevalence medicine Animals education Escherichia coli Infections Dairy cattle media_common education.field_of_study Antimicrobial Anti-Bacterial Agents Cross-Sectional Studies Cattle Animal Science and Zoology medicine.drug |
| Zdroj: | Preventive Veterinary Medicine. 142:39-45 |
| ISSN: | 0167-5877 |
| DOI: | 10.1016/j.prevetmed.2017.05.003 |
| Popis: | Resistance to third-generation cephalosporins and other beta-lactam antibiotics is of major concern for animal and human health. Knowledge of the prevalence of resistant bacteria in primary production is an important element to estimate transmission along the stages in the food production chain and the exposure of the human population. The primary objective of this study was to determine the prevalence of cefotaxime-resistant commensal E. coli in dairy and beef cattle production units throughout Germany. Secondarily, the association between management factors and the presence of cefotaxime resistance was investigated. In total, 60 beef cattle and 52 dairy cattle production units all over Germany were included. Cefotaxime-resistant E. coli were isolated from at least one sample in 70% (95% CI: 58–83%) of the farms keeping beef cattle and 85% (95% CI: 75–94%) of the farms keeping dairy cattle. The sample prevalence was 35% (161/455; 95% CI: 31–40%) and 48% (156/323; 95% CI: 43–54%), respectively. Most factors associated with resistance to cefotaxime indicate that less intensive production results in a lower number of positive samples. For beef cattle, antimicrobial treatment of the whole animal group was significantly associated with an increased proportion of samples containing cefotaxime resistant E. coli. In addition, our results indicate that better hygiene management could improve the resistance situation on cattle farms. |
| Databáze: | OpenAIRE |
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