Long-term follow-up after coronary stenting and intravascular red laser therapy
| Autor: | Michael H. Keelan, Victor V. Nikolaychik, Nicholas Kipshidze, Kai Wang, Ivan De Scheerder, Harry Sahota, Upendra Kaul, Balbir Singh |
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| Rok vydání: | 2000 |
| Předmět: |
Male
medicine.medical_specialty Angioplasty Balloon Laser-Assisted medicine.medical_treatment Coronary Disease Coronary Angiography Severity of Illness Index Lesion Restenosis Angioplasty Internal medicine medicine Humans Red light Adverse effect Vascular Patency Aged business.industry Graft Occlusion Vascular Coronary stenting Middle Aged medicine.disease medicine.anatomical_structure Treatment Outcome Cardiology Female Stents medicine.symptom Cardiology and Cardiovascular Medicine business Complication Artery Follow-Up Studies |
| Zdroj: | The American journal of cardiology. 86(9) |
| ISSN: | 0002-9149 |
| Popis: | A high restenosis rate remains a limiting factor for coronary angioplasty and stenting. Recently, use of intravascular red light therapy (IRLT) has been shown to be effective in different animal models and in humans in reducing the restenosis rate. Sixty-eight patients were treated with IRLT in conjunction with coronary stenting procedures. Mean age was 64 +/- 9 years. Treated lesions were type A (11), type B (42), and type C (18) with a mean lesion length of 16.5 +/- 2.4 mm. Reference vessel diameter and minimal lumen diameter (MLD) before therapy were 2.90 +/- 0.15 and 1.12 +/- 0.36 mm, respectively. After stenting and laser irradiation, MLD was 2.76 +/- 0.39 mm. No procedural complications or in-hospital adverse events occurred. All patients were followed up as depicted in the protocol. Sixty-one patients underwent angiographic restudy, which revealed restenosis in 9 patients (14.7%). Observed restenosis rate by artery size was3 mm (n = 21, 0%), 2.5 to 3.0 mm (n = 28, 14.2%), and2.5 mm (n = 12, 41.6%). We conclude that IRLT is safe and feasible and reduces the expected restenosis rate in patients after coronary stenting in arteries of2.5 mm. |
| Databáze: | OpenAIRE |
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