Epidemiology of Helicobacter pylori Infection in the Czech Republic
| Autor: | Marcela Kopáčová, Tomáš Douda, Pavel Zivny, M. Pintér, Ilona Koupil, Vladimir Palicka, O. Pozler, Viktor Vorisek, Jan Bures, Bohumil Seifert, Stanislav Rejchrt, Martin Beranek, Jan Holčík, Martina Kolesárová |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male Czech Helicobacter pylori infection medicine.medical_specialty Pediatrics Adolescent Population Social class Helicobacter Infections 03 medical and health sciences 0302 clinical medicine Epidemiology Prevalence Humans Medicine 030212 general & internal medicine Child education Socioeconomic status Aged Czech Republic Aged 80 and over Breath test education.field_of_study Helicobacter pylori biology medicine.diagnostic_test business.industry 1. No poverty Gastroenterology General Medicine Middle Aged biology.organism_classification language.human_language Anti-Bacterial Agents 3. Good health Infectious Diseases Breath Tests Social Class language Educational Status Female 030211 gastroenterology & hepatology business Demography |
| Zdroj: | Helicobacter. 11:56-65 |
| ISSN: | 1523-5378 1083-4389 |
| Popis: | Background: Prevalence of Helicobacter pylori infection has been estimated to range from 60 to 95% in the former communist countries of Central and Eastern Europe. The aim of this study was to evaluate H. pylori infection prevalence in a representative sample of the Czech population. The second objective was to describe difference of H. pylori prevalence between different social groups of children and adults. Materials and Methods: A total of 2509 persons aged 5–100 years, randomly selected out of 30,012 persons of the general population, took part in the study. H. pylori infection was investigated by means of 13C-urea breath test. Breath samples were analyzed by isotope ratio mass spectrometry. Social and demographic characteristics were based on data from self-completed questionnaires. Results: Using the total Czech population as a standard, we estimated the age-standardized prevalence of H. pylori in males aged 5+ years at 41.9% (95% CI 39.0%, 44.8%) and in females aged 5+ years at 41.4% (95% CI 38.6%, 44.3%) in 2001. Prevalence of H. pylori increased with age but was not related to gender. Children of mothers with basic or lower education, living in crowded accommodations, without access to running warm water, and residing in smaller towns appear to be at the highest risk. Low education and heavy smoking are most strongly associated with prevalence of H. pylori positivity in adults and adolescents. Conclusions: This is a unique study based on a representative sample of the general population in a Central European country. The overall prevalence of H. pylori is lower than previously assumed and could partly reflect a substantial recent decrease in H. pylori prevalence in the Czech Republic. Consistent with earlier studies, H. pylori infection is strongly influenced by socioeconomic conditions and childhood poverty. |
| Databáze: | OpenAIRE |
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