Biologically Active Triterpene Saponins fromBupleurum fruticosum
| ISSN: | 1439-0221 0032-0943 |
|---|---|
| Přístupová URL adresa: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ded02cc012d352a514b27bdd196036f2 https://doi.org/10.1055/s-2006-959442 |
| Přírůstkové číslo: | edsair.doi.dedup.....ded02cc012d352a514b27bdd196036f2 |
| Autor: | Parellada J, Lacaille-Dubois Ma, Wagner H, Guinea Mc |
| Rok vydání: | 1994 |
| Předmět: |
Molecular Sequence Data
Saponin Pharmaceutical Science Bupleurum fruticosum Saccharomyces cerevisiae In Vitro Techniques Aminopeptidase Analytical Chemistry Hemolysin Proteins Leucyl Aminopeptidase Phagocytosis Triterpene Drug Discovery Animals Humans Leucyl aminopeptidase Cells Cultured Pharmacology chemistry.chemical_classification Plants Medicinal Apiaceae biology Organic Chemistry Biological activity Saponins biology.organism_classification Triterpenes Terpenoid Rats Carbohydrate Sequence Liver Complementary and alternative medicine chemistry Biochemistry Molecular Medicine |
| Zdroj: | Planta Medica. 60:163-167 |
| ISSN: | 1439-0221 0032-0943 |
| Popis: | Extracts of the root of B. fruticosum L. showed in a biological screening hemolytical activity, hepatoprotective and phagocytosis stimulating effects, and a specific inhibitory activity of leucine aminopeptidase. Further monitoring of the fraction with antihepatotoxic activity led to the isolation of an hepatoprotective saikosaponin identified as buddlejasaponin IV and the new malonylbuddlejasaponin IV, determined as saikogenin F-3-O-[6-O-malonyl-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl (1-->3)]-beta-D-fucopyranoside. The structures were elucidated on the basis of the chemical and spectroscopic data. |
| Databáze: | OpenAIRE |
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