Validity of International Classification of Diseases, Tenth Revision, Codes for Cirrhosis
| Autor: | Michael H. Le, Nathan S. Ramrakhiani, An K. Le, Yee Hui Yeo, Mindie H. Nguyen, Mayumi Maeda |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Liver Cirrhosis Male medicine.medical_specialty Cirrhosis Population Chronic liver disease Cohort Studies 03 medical and health sciences Liver disease 0302 clinical medicine International Classification of Diseases Predictive Value of Tests Internal medicine medicine Humans education Hepatitis education.field_of_study Receiver operating characteristic business.industry Gastroenterology Reproducibility of Results General Medicine Middle Aged medicine.disease ROC Curve 030220 oncology & carcinogenesis Cohort 030211 gastroenterology & hepatology Female Diagnosis code business Liver: Research Article |
| Zdroj: | Dig Dis |
| ISSN: | 1421-9875 |
| Popis: | Introduction: Accurate identification of patients with cirrhosis is important for research using administrative databases. We aimed to examine the accuracy of several major ICD-10 codes for cirrhosis diagnosis in a large and diverse patient cohort; there is little existing research on this topic. Methods: Using data from 3,396 patients with chronic liver disease (hepatitis B or C or nonalcoholic fatty liver disease) from 1 university and several community medical centers, we calculated sensitivity, specificity, positive predictive value (PPV), negative predictive value, and area under the receiver operating characteristic curve (AUROC) for several major ICD-10 codes for cirrhosis, which was verified by individual chart review. We performed a secondary validation in a general cohort of 1,560 randomly selected patients. Results: While each of the individual study ICD-10 codes were specific (98.08–100%), none of the codes were sufficiently sensitive (0.27–55.70%). PPVs were high in the chronic liver disease cohort (88.41–100%) but lower in the general population (55.53–66.76%). The AUROC for having at least 1 code was higher (0.79) than any code alone (0.50–0.65). Discussion/Conclusion: Individual ICD-10 codes are suboptimal for identifying patients with cirrhosis in the general patient population. We recommend conditioning ICD-10 code searches with a chronic liver disease diagnosis code and/or combining diagnostic codes to maximize performance. |
| Databáze: | OpenAIRE |
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