Elementary motion sequence detectors in whisker somatosensory cortex
| Autor: | Tomer Langberg, Daniel E. Feldman, Keven J. Laboy-Juárez, Seoiyoung Ahn |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Computation Feature extraction Motion (geometry) integration cortical column Somatosensory system Article 03 medical and health sciences Mice 0302 clinical medicine tactile sensation tuning Whisker motion rate code Animals Psychology Physics Sequence Neurology & Neurosurgery Basis (linear algebra) General Neuroscience Detector Neurosciences Somatosensory Cortex surround suppression 030104 developmental biology Touch Perception Touch Vibrissae nonlinear Cognitive Sciences Biological system Neuroscience Mechanoreceptors 030217 neurology & neurosurgery |
| Zdroj: | Nature neuroscience, vol 22, iss 9 Nature neuroscience |
| Popis: | How the somatosensory cortex (S1) encodes complex patterns of touch, such as those that occur during tactile exploration, is poorly understood. In the mouse whisker S1, temporally dense stimulation of local whisker pairs revealed that most neurons are not classical single-whisker feature detectors, but instead are strongly tuned to two-whisker sequences that involve the columnar whisker (CW) and one specific surround whisker (SW), usually in a SW-leading-CW order. Tuning was spatiotemporally precise and diverse across cells, generating a rate code for local motion vectors defined by SW-CW combinations. Spatially asymmetric, sublinear suppression for suboptimal combinations and near-linearity for preferred combinations sharpened combination tuning relative to linearly predicted tuning. This resembles computation of motion direction selectivity in vision. SW-tuned neurons, misplaced in the classical whisker map, had the strongest combination tuning. Thus, each S1 column contains a rate code for local motion sequences involving the CW, thus providing a basis for higher-order feature extraction. |
| Databáze: | OpenAIRE |
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