Prediction and follow-up of risk factors for severe SARS-CoV-2 pneumonia and application of CT visual scoring

Autor: Li Zhang, Xiaxia Wu, Xiu-Mei Li, Zhibing He, Yingjian Ye, Chun-Mei Xu, Qiongxia Li, Bo Liu, Huan Li, Wenhuan Yuan, Lishi Zheng, Qingpeng Wang
Rok vydání: 2021
Předmět:
Adult
Male
China
medicine.medical_specialty
Pneumonia
Viral
Biomedical Engineering
Biophysics
Health Informatics
Bioengineering
Comorbidity
Logistic regression
Severity of Illness Index
Body Mass Index
030218 nuclear medicine & medical imaging
Pulmonary function testing
Biomaterials
03 medical and health sciences
0302 clinical medicine
Risk Factors
Internal medicine
Severity of illness
medicine
Humans
030212 general & internal medicine
Lung
Aged
Retrospective Studies
Hematologic Tests
medicine.diagnostic_test
Receiver operating characteristic
SARS-CoV-2
business.industry
COVID-19
Retrospective cohort study
Length of Stay
Middle Aged
Prognosis
medicine.disease
Pneumonia
Logistic Models
ROC Curve
Erythrocyte sedimentation rate
Disease Progression
Female
Tomography
X-Ray Computed
business
Body mass index
Research Article
Information Systems
Zdroj: Technology and Health Care
ISSN: 1878-7401
0928-7329
DOI: 10.3233/thc-218016
Popis: BACKGROUND: The SARS-CoV-2 pneumonia infection is associated with high rates of hospitalization and mortality and this has placed healthcare systems under strain. Our study provides a novel method for the progress prediction, clinical treatment and prognosis of NCP, and has important clinical value for timely treatment of severe NCP patients. OBJECTIVE: To summarize the clinical features and severe illness risk factors of the patients with novel coronavirus pneumonia (NCP), in order to provide support for the progression prediction, clinical treatment and prognosis of NCP patients. MATERIALS AND METHODS: A total of 196 NCP patients treated in our hospital from January 25, 2020 to June 21, 2020 were divided into the severe group and the mild group. The clinical features of the two groups were analyzed and compared. The risk factors were explored by using multivariate logistic regression, and the receiver operating characteristic (ROC) curve was obtained. The correlations of the risk factors with the prognosis of NCP were investigated combined with the lung function test. RESULTS: The primary clinical symptoms of 196 cases of NCP included fever in 167 cases (85.2%) and cough in 121 cases (61.73%). The chest computed tomography (CT) scans of the 178 cases (90.81%) showed a typical ground-glass opacification. In 149 cases, the lymphocyte count was decreased, while the levels of creatine kinase (CK), lactate dehydrogenase (LDH), c-reactive protein (CRP), erythrocyte sedimentation rate (ESR) and D-dimer (D-D) increased. 44 cases (22.45%) were found to be severely ill. The multivariate logistic regression analysis demonstrated that age, underlying disease, length of hospital stay, body mass index (BMI), LDH, chest CT visual score, absolute lymphocyte count (ALC) and CRP were risk factors for severe
Databáze: OpenAIRE
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