Refractory Adult Primary Autoimmune Neutropenia that Responded to Alemtuzumab
| Autor: | Fengshuo Lan, Takeshi Saraya, Anu Radha Neerukonda, Theodore G. Gabig |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Neutropenia 030204 cardiovascular system & hematology Granulocyte Antibodies Monoclonal Humanized Gastroenterology White People Autoimmune Diseases 03 medical and health sciences 0302 clinical medicine Refractory Internal medicine Internal Medicine medicine Humans Medical history biology business.industry food and beverages General Medicine medicine.disease medicine.anatomical_structure Treatment Outcome Autoimmune neutropenia Monoclonal biology.protein Alemtuzumab Female Antibody business 030215 immunology Rare disease medicine.drug |
| Zdroj: | Internal medicine (Tokyo, Japan). 55(12) |
| ISSN: | 1349-7235 |
| Popis: | Primary autoimmune neutropenia (P-AIN) is an extremely rare disease. The most effective treatment for primary P-AIN is a granulocyte colony-stimulating factor; however, no curative treatment has been reported. We herein report a case of an adult P-AIN patient with a relatively mild medical history (irrespective of the severe neutropenia) who showed a sustained hematological response over seventeen months after the initiation of treatment with subcutaneous Alemtuzumab. |
| Databáze: | OpenAIRE |
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