ISOLATED DIASTOLIC DYSFUNCTION AS A RESULT OF HYPERNITRICOXIDEMIA IN ARTERIAL HYPOTENSION

Autor: V. M. Baev, T. Yu. Agafonova, O. A. Samsonova, R. Sh. Dusakova
Rok vydání: 2017
Předmět:
Zdroj: Кардиоваскулярная терапия и профилактика, Vol 16, Iss 5, Pp 16-19 (2017)
ISSN: 1728-8800
DOI: 10.15829/1728-8800-2017-5-16-19
Popis: Aim. The assessment of cardiac hemodynamics in the test with reactive hyperemia in young females with idiopathic arterial hypotension. Material and methods . The comparative analysis was done, of echocardiography in the standard test with reactive hyperemia within brachial area among 72 women with idiopathic arterial hypotension — systolic blood pressure 94-98 mmHg, and in 37 females normotensive — systolic BP 120-123 mmHg. In both groups the age was 19 (18-22) y.o. Results . Reactive hyperemia in hypotension is followed by a significant increase of maximum velocities relation of the early (peak E) and delayed (peak A) diastolic filling of the left ventricle by 18%. In normotensive women there was no such change of the relation. Conclusion . In young females with idiopathic arterial hypotension the test with reactive hyperemia, as a model of acute hypoxia, is followed by isolated diastolic dysfunction of myocardium. Probably, it is related to the increase of the rate of already existing hypernitricoxidemia, which is a key factors for arterial hypotension pathogenesis.
Databáze: OpenAIRE