Streptococcus pneumoniaecarriage and penicillin/ ceftriaxone resistance in hospitalised children in Darwin

Autor: A. J. Leach, B. J. Currie, S. A. Skull
Rok vydání: 1996
Předmět:
Zdroj: Australian and New Zealand Journal of Medicine. 26:391-395
ISSN: 0004-8291
DOI: 10.1111/j.1445-5994.1996.tb01928.x
Popis: Background: The prevalence of resistant Streptococcus pneumoniae (SP) is increasing worldwide. Pneumococcal prevalence and susceptibility patterns are not known for children in the Top End of the Northern Territory. Aims: To determine the prevalence of nasopharyngeal carriage of pneumococci in children hospitalised in Darwin, and the extent of penicillin and ceftriaxone resistance in these isolates. Methods: Nasopharyngeal swabs were collected on admission from 85 children who had not received antimicrobials for their admission illness. Antimicrobial resistance was determined following selective culture for SP isolates. Minimal inhibitory concentrations (MICs) for penicillin and ceftriaxone were determined using the E-test method. Results: The overall prevalence of nasopharyngeal SP carriage was 44%. Carriage occurred more often in Aboriginal children from rural areas (56%) than in urban children (24%) (OR 3.94, 95% CI 1.35 - 11.78, p
Databáze: OpenAIRE