Characterizing the small RNA transcriptome associated with COPD and ILD using next-generation sequencing
| Autor: | Mick Correll, John Tedrow, Joseph Gerrein, John Quackenbush, Lingqi Luo, Gang Liu, Ji Xiao, Jennifer Beane, Marc E. Lenburg, Brenda Juan Guardela, David A. Schwartz, Yuriy Aleksyev, Naftali Kaminski, Avrum Spira, Joshua D. Campbell, Frank C. Sciurba, Ivana V. Yang, Mark W. Geraci |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Small RNA
COPD Lung business.industry Interstitial lung disease Library science General Medicine respiratory system Bioinformatics medicine.disease General Biochemistry Genetics and Molecular Biology DNA sequencing respiratory tract diseases Transcriptome Pathogenesis medicine.anatomical_structure microRNA Poster Presentation Medicine business |
| Zdroj: | BMC Proceedings |
| ISSN: | 1753-6561 |
| Popis: | Background Despite the increasing public health burden associated with chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD), the molecular mechanisms responsible for the pathogenesis of these diseases remain unclear. The goal of this study was to comprehensively profile the lung small RNA transcriptome via next-generation sequencing, and elucidate microRNAs that might contribute to COPD and ILD pathogenesis. |
| Databáze: | OpenAIRE |
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