Assignment of a gene for uridine diphosphate galactose-4-epimerase to human chromosome 1 by somatic cell hybridization, with evidence for a regional assignment to 1pter→1p21
| Autor: | Thomas B. Shows, William J. Mellman, K.G. Orkwiszewski, Peter Benn, Carlo M. Croce, G.G. D’Ancona |
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| Rok vydání: | 1979 |
| Předmět: |
Genetics
Somatic Cell Hybrids Chromosomes Human 1-3 Chromosome Mapping Chromosome Uridine diphosphate galactose-4-epimerase Hybrid Cells Biology Somatic Cell Hybridization Molecular biology carbohydrates (lipids) Mice UDPglucose 4-Epimerase Uridine diphosphate chemistry.chemical_compound chemistry Animals Humans Carbohydrate Epimerases Molecular Biology Gene Genetics (clinical) |
| Zdroj: | Cytogenetic and Genome Research. 24:138-142 |
| ISSN: | 1424-859X 1424-8581 |
| DOI: | 10.1159/000131369 |
| Popis: | The presence of human uridine diphosphate galactose-4-epimerase (GALE) was found to correlate with the presence of chromosome 1 in somatic cell hybrids between man and mouse. The gene for GALE can therefore be assigned to human chromosome 1. Using a chromosome 1 rearrangement, we have been able to regionally assign GALE to the pter→p21 region. |
| Databáze: | OpenAIRE |
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