Facile synthesis of 1,4-cis-polyisoprene–polypeptide hybrids with different architectures
| Autor: | Amélie Vax, Frédéric Peruch, François Jean-Baptiste-Dit-Dominique, Jérémie Grange, Stéphane Grelier, Alexei V. Radchenko, Rachid Matmour |
|---|---|
| Přispěvatelé: | Team 1 LCPO : Polymerization Catalyses & Engineering, Laboratoire de Chimie des Polymères Organiques (LCPO), Centre National de la Recherche Scientifique (CNRS)-Institut Polytechnique de Bordeaux-Ecole Nationale Supérieure de Chimie, de Biologie et de Physique (ENSCBP)-Université de Bordeaux (UB)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut Polytechnique de Bordeaux-Ecole Nationale Supérieure de Chimie, de Biologie et de Physique (ENSCBP)-Université de Bordeaux (UB)-Institut de Chimie du CNRS (INC), Société Michelin, Team 2 LCPO : Biopolymers & Bio-sourced Polymers |
| Rok vydání: | 2019 |
| Předmět: |
chemistry.chemical_classification
Molar mass Polymers and Plastics Organic Chemistry Bioengineering 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Biochemistry Aldehyde Reductive amination 0104 chemical sciences Catalysis chemistry.chemical_compound [CHIM.POLY]Chemical Sciences/Polymers Monomer chemistry Polymerization Thiourea Polymer chemistry Copolymer 0210 nano-technology |
| Zdroj: | Polymer Chemistry Polymer Chemistry, Royal Society of Chemistry-RSC, 2019, 10 (19), pp.2456-2468. ⟨10.1039/c9py00241c⟩ |
| ISSN: | 1759-9962 1759-9954 |
| DOI: | 10.1039/c9py00241c |
| Popis: | International audience; The synthesis of polypeptide hybrids by controlled/living ring-opening polymerization of N-carboxyanhydrides (NCA) using Schreiner′s thiourea catalyst and amino-alcohol terminated poly(1,4-cis-isoprene)s as initiators was demonstrated for γ-benzyl-ʟ-glutamate (BLG) and ε-tert-butyloxycarbonyl-ʟ-lysine (BLL) NCAs. One-pot synthesis of amino-alcohol terminated macroinitiators from heterotelechelic keto/aldehyde polyisoprene by reductive amination of carbonyl(s) was presented. Selection of amines allowed to obtain mono-, di-and tri-functional macroinitiators that were used for the synthesis of polyisoprene-polypeptide hybrids of different architecture: AB, BAB, AB2, BAB2, CBABC. Due to the living character of the polymerization, the molar mass of the polypeptide blocks could be controlled by the monomer to initiator ratio (6000 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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