Multicomponent Synthesis of Tetrahydroisoquinolines

Autor:	Sunliang Cui, Yangyong Shen, Bo Huang, Linwei Zeng
Rok vydání:	2018
Předmět:	Reaction mechanism 010405 organic chemistry Chemistry Organic Chemistry Structural diversity Molecule Physical and Theoretical Chemistry 010402 general chemistry 01 natural sciences Biochemistry Combinatorial chemistry 0104 chemical sciences
Zdroj:	Organic letters. 20(12)
ISSN:	1523-7052
Popis:	A multicomponent synthesis of tetrahydroisoquinolines from carboxylic acids, alkynyl ethers, and dihydroisoquinolines is described. This process features readily available starting materials, simple experimental procedures for achievement of molecule complexity, and structural diversity. The preliminary control experiment and crossover reaction provide important insight into the reaction mechanism. The formed tetrahydroisoquinolines could be transformed to an array of compounds.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7e379b8a0569fcfb6e59cf4ab8cb20 https://pubmed.ncbi.nlm.nih.gov/29809014 Zobrazit plný text záznamu