Acute Liver Failure
Autor: | Curtis Barry, Carmi Punzalan |
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Rok vydání: | 2016 |
Předmět: |
medicine.medical_specialty
Pathology medicine.medical_treatment Liver transplantation Critical Care and Intensive Care Medicine Gastroenterology 03 medical and health sciences Liver disease 0302 clinical medicine Internal medicine medicine Coagulopathy Hepatic encephalopathy Liver injury medicine.diagnostic_test business.industry digestive oral and skin physiology Jaundice medicine.disease 3. Good health Acetaminophen 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology medicine.symptom business Liver function tests medicine.drug |
Zdroj: | Journal of Intensive Care Medicine. 31:642-653 |
ISSN: | 1525-1489 0885-0666 |
DOI: | 10.1177/0885066615609271 |
Popis: | Acute liver failure is life threatening liver injury with coagulopathy and hepatic encephalopathy within 26 weeks and generally, in the absence of preexisting liver disease. Fulminant liver failure occurs when hepatic encephalopathy occurs within 8 weeks of jaundice. The majority of patients with ALF are women with the median age of 38 years. In the United States, drug induced liver injury including acetaminophen causes the majority of ALF cases. The etiology of ALF should be determined, if possible, because many causes have a specific treatment. The mainstay for ALF is supportive care and liver transplantation, if necessary. There are multiple prognostic criteria available. Prognosis can be poor and patients should be referred to a liver transplantation center as soon as possible. |
Databáze: | OpenAIRE |
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