Acute Liver Failure

Autor: Curtis Barry, Carmi Punzalan
Rok vydání: 2016
Předmět:
Zdroj: Journal of Intensive Care Medicine. 31:642-653
ISSN: 1525-1489
0885-0666
DOI: 10.1177/0885066615609271
Popis: Acute liver failure is life threatening liver injury with coagulopathy and hepatic encephalopathy within 26 weeks and generally, in the absence of preexisting liver disease. Fulminant liver failure occurs when hepatic encephalopathy occurs within 8 weeks of jaundice. The majority of patients with ALF are women with the median age of 38 years. In the United States, drug induced liver injury including acetaminophen causes the majority of ALF cases. The etiology of ALF should be determined, if possible, because many causes have a specific treatment. The mainstay for ALF is supportive care and liver transplantation, if necessary. There are multiple prognostic criteria available. Prognosis can be poor and patients should be referred to a liver transplantation center as soon as possible.
Databáze: OpenAIRE