Locally extensive meningoencephalitis caused by Miamiensis avidus (syn. Philasterides dicentrarchi) in a zebra shark
| Autor: | Wen-Ta Li, Hui-Wei Chang, Hsuan Kuo, Chen-Yi Su, Chian-Ren Jeng, Susanne Je-Han Lin, Chieh Lo, Victor Fei Pang |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
040301 veterinary sciences Parasitic Diseases Animal Aquatic Science Biology law.invention Microbiology 0403 veterinary science 03 medical and health sciences Fish Diseases Fatal Outcome law Meningoencephalitis medicine Animals Myxozoa Gene Ecology Evolution Behavior and Systematics Polymerase chain reaction 04 agricultural and veterinary sciences Ribosomal RNA Amplicon medicine.disease biology.organism_classification Virology 030104 developmental biology Tissue tropism Sharks Protozoa Female Meningitis |
| Zdroj: | Diseases of aquatic organisms. 126(2) |
| ISSN: | 0177-5103 |
| Popis: | Scuticociliatosis, caused by ciliated protozoa in the subclass Scuticociliatia of the phylum Ciliophora, can cause fatal disease in teleost fish species. However, information on scuticociliatosis in elasmobranchs is still scarce. In this report, we describe a case of locally extensive meningoencephalitis caused by Miamiensis avidus (syn. Philasterides dicentrarchi) in a 2 yr old captive zebra shark Stegostoma fasciatum. Granulocytic meningoencephalitis was observed through histological assessment. Inflammation was confined to the ventral aspect of the brain with a large number of ciliated protozoa, transforming into non-suppurative meningitis in the lateral aspect, and gradually vanished in the dorsal aspect. No histopathological and polymerase chain reaction (PCR) evidence of systemic dissemination of M. avidus was found. PCR targeting the gene coding the small-subunit ribosomal RNA (SSUrRNA) of M. avidus was performed on the brain, liver, and gill tissues, and only brain tissue yielded a positive result. The DNA sequences from amplicons of the protozoal SSUrRNA gene were completely matched to that of M. avidus. The distribution of protozoa in the current case was mainly located in the brain and suggests the possibility of a direct neural invasive pathway of M. avidus through the nasal cavity/ampullary system and/or a unique tissue tropism of M. avidus specific to the brain in zebra sharks. Further investigations on the pathogenesis of M. avidus in elasmobranchs, especially zebra sharks, are needed. |
| Databáze: | OpenAIRE |
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