Measles in the 21st Century: Progress Toward Achieving and Sustaining Elimination

Autor: Walt Orenstein, Manisha Patel, Paul A Gastañaduy, Paul A. Rota, Lakshmi Panagiotakopoulos, James L. Goodson
Rok vydání: 2021
Předmět:
Zdroj: The Journal of Infectious Diseases
ISSN: 1537-6613
0022-1899
DOI: 10.1093/infdis/jiaa793
Popis: The global measles vaccination program has been extraordinarily successful in reducing measles-related disease and deaths worldwide. Eradication of measles is feasible because of several key attributes, including humans as the only reservoir for the virus, broad access to diagnostic tools that can rapidly detect measles-infectious persons, and availability of highly safe and effective measles-containing vaccines (MCVs). All 6 World Health Organization (WHO) regions have established measles elimination goals. Globally, during 2000–2018, measles incidence decreased by 66% (from 145 to 49 cases per million population) and deaths decreased by 73% (from 535 600 to 142 300), drastically reducing global disease burden. Routine immunization with MCV has been the cornerstone for the control and prevention of measles. Two doses of MCV are 97% effective in preventing measles, qualifying MCV as one of the most effective vaccines ever developed. Mild adverse events occur in
Databáze: OpenAIRE