An unusual familial cardiomyopathy characterized by aberrant accumulations of desmin-type intermediate filaments
| Autor: | A. Porte, Marie-Elisabeth Stoeckel, André Sacrez, Klaus Weber, André Batzenschlager, Mary Osborn |
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| Rok vydání: | 1981 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Histology Cardiomyopathy macromolecular substances Immunofluorescence Microscopy Immunofluorescence Pathology and Forensic Medicine medicine Humans Intermediate filament Molecular Biology Cytoskeleton medicine.diagnostic_test Chemistry Muscles Myocardium Familial cardiomyopathy Cardiac muscle Cardiac ultrastructure Cell Biology General Medicine medicine.disease Cell biology Microscopy Electron medicine.anatomical_structure Desmin Anatomy Cardiomyopathies |
| Zdroj: | Virchows Archiv A Pathological Anatomy and Histology. 393:53-60 |
| ISSN: | 1432-2307 0340-1227 |
| DOI: | 10.1007/bf00430870 |
| Popis: | Immunofluorescence microscopy using antibodies specific for different intermediate filament types has been used to study a rare familial cardiomyopathy characterized electron microscopically by massive accumulations of unordered intermediate filaments. The results show that the inclusions in cardiac muscle cells are composed of the desmin type of intermediate filament characteristic of muscle tissues, and draw attention to the importance of these filaments in maintaining normal cardiac ultrastructure and function. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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