Heterocyclic Trost’s ligands. Synthesis and applications in asymmetric allylic alkylation

Autor: Angelica Konovets, Nathalie Percina-Pichon, Alexander Iourtchenko, Denis Sinou
Rok vydání: 2004
Předmět:
Zdroj: ARKIVOC, Vol 2004, Iss 14, Pp 103-109 (2004)
ISSN: 1551-7012
DOI: 10.3998/ark.5550190.0005.e11
Popis: Condensation of (1R,2R)-1,2-diaminocyclohexane with 2-(diphenylphosphino)nicotinic acid and 3-(diphenylphosphino)quinoxaline-2-carboxylic acid afforded the corresponding diphosphines. These ligands were used in the palladium-catalyzed alkylation of various allylic acetates with carbon and nitrogen nucleophiles, giving generally lower enantioselectivities than the analogous non-heterocyclic ligands.
Databáze: OpenAIRE