Effects of intensity-matched exercise at different intensities on inflammatory responses in able-bodied and spinal cord injured individuals
| Autor: | Ronaldo Vagner Thomatiele dos Santos, Fábio Santos Lira, Sergio Tufik, Marco Túlio de Mello, Alexandre Aparecido de Almeida, Kate M. Edwards, Mateus J. Benvenutti, Eduardo da Silva Alves |
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| Přispěvatelé: | Universidade Estadual de Santa Cruz–(UESC), Universidade Federal de São Paulo (UNIFESP), Centro de Estudos em Psicobiologia e Exercício - CEPE, Universidade Estadual Paulista (Unesp), Ciência e Tecnologia do Tocantins, University of Sydney, Universidade Estadual de Maringá (UEM), Universidade Federal de Minas Gerais (UFMG) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_treatment
Inflammation Proinflammatory cytokine 03 medical and health sciences 0302 clinical medicine Spinal cord injuries Medicine Humans Exercise Spinal Cord Injuries Research Articles Acute physical exercise Paraplegia Rehabilitation business.industry Interleukin-6 030229 sport sciences Spinal cord Intensity (physics) Exercise Therapy medicine.anatomical_structure Anesthesia Cytokines Neurology (clinical) medicine.symptom business 030217 neurology & neurosurgery Brazil |
| Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP J Spinal Cord Med |
| ISSN: | 1111-1232 |
| Popis: | Made available in DSpace on 2020-12-12T01:21:13Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01 Objective: To compare the effects of intensity-matched acute exercise at different intensities on proinflammatory and anti-inflammatory cytokines between able-bodied (AB) and spinal cord injured (SCI) individuals. Design: Non-Randomized Controlled Trial. Setting: Community settings in São Paulo–Brazil. Participants: Eight AB and nine SCI paraplegic. Interventions: Participants underwent three exercise sessions at different relative intensities: at ventilatory threshold 1 intensity (VT1), 15% below VT1, and 15% above VT1. Similar energy expenditures were established from exercises with different intensities for each volunteer. The AB group was tested on a conventional treadmill, whereas the SCI group was tested on a treadmill adapted for wheelchair use. Blood samples were collected at baseline, immediately after, and 30 min after the exercise sessions. Outcome measures: Interleukin 1 receptor antagonist, interleukin 1 beta, interleukin 2, interleukin 4, interleukin 6, interleukin 10 and tumoral necrosis factor alpha were measured. Results: When groups were compared, interleukin–2 was found higher, whereas interleukin–4 and interleukin–10 were found lower in the SCI group at all collection times in the three exercise intensities (all P < 0.05). Interleukin–1 receptor antagonist was found higher immediately after exercise at VT1, 15% above VT1 and 30 min after 15% below VT1 in the AB group (all P < 0.05). In the AB group, an increase in interleukin–6 immediately after the exercise at VT1 compared with baseline was found (P = 0.01). Conclusion: Individuals with SCI may have to perform physical exercise at a higher volume or energy expenditure than AB individuals to obtain similar anti-inflammatory benefits of acute exercise. Trial registration: Uniform Trial Number identifier: U1111-1232-8142. Departamento de Ciências da Saúde Universidade Estadual de Santa Cruz–(UESC) Departamento de Psicobiologia Universidade Federal de São Paulo–(UNIFESP) Centro de Estudos em Psicobiologia e Exercício - CEPE Department of Physical Education Universidade Estadual Paulista (UNESP) Instituto Federal de Educação Ciência e Tecnologia do Tocantins Campus Araguatins Faculty of Health Sciences University of Sydney Departamento de Biociências e Fisiopatologia Universidade Estadual de Maringá–UEM Escola de Educação Física Fisioterapia e Terapia Ocupacional Universidade Federal de Minas Gerais - UFMG Department of Physical Education Universidade Estadual Paulista (UNESP) |
| Databáze: | OpenAIRE |
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