Electrocardiographic precordial mapping in anterior myocardial infarction. The critical period for interventions as exemplified by methylprednisolone
| Autor: | E. Welman, A. Jonathan, K. M. Fox, Andrew P. Selwyn, J. P. Shillingford |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Myocardial Infarction Ischemia Infarction Anterior myocardial infarction Precordial examination Chest pain Methylprednisolone Electrocardiography Heart Conduction System Physiology (medical) Internal medicine medicine Humans ST segment Aged business.industry ST elevation Middle Aged medicine.disease Cardiology Drug Evaluation Regression Analysis Female medicine.symptom Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | Circulation. 58:892-897 |
| ISSN: | 1524-4539 0009-7322 |
| DOI: | 10.1161/01.cir.58.5.892 |
| Popis: | Serial 72-point precordial mapping of ECG has been recorded to describe the natural history of changes in the precordial areas of ST segment elevation and the development of Q waves in 51 patients with acute uncomplicated anterior myocardial infarction. Eight patients have been studied in the same way but received 25 mg/kg of methylprednisolone sodium succinate as a single intravenous injection within 6 hours from the onset of chest pain. There was a linear relationship between the stable precordial area of Q waves at 24 hours and the rapidly changing precordial areas of ST segment elevation at 2--3 hours, 5--6 hours and 12 hours after the onset of pain in the untreated patients. When methylprednisolone was given, the treated patients developed a smaller precordial area of Q waves at 24 hours than was predicted from the precordial area of ST elevation recorded before the drug was given. This study has introduced a technique that can provide a qualitative assessment of the relationship between ECG evidence of ischemia and infarction in each patient. |
| Databáze: | OpenAIRE |
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