Molecular Aspects in the Potential of Vitamins and Supplements for Treating Diabetic Neuropathy
| Autor: | Tina Okdahl, Christina Brock |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Diabetic neuropathy
Endocrinology Diabetes and Metabolism Bioinformatics Neuroprotection Antioxidants law.invention Dietary supplement Effective interventions Diabetic Neuropathies Randomized controlled trial law Diabetes mellitus Diabetes Mellitus Internal Medicine medicine Humans Tight glucose control Vitamin A Clinical Trials as Topic business.industry Vitamins medicine.disease Clinical trial Dietary Supplements Nerve conduction business Microvascular Complications—Neuropathy (R Pop-Busui Section Editor) |
| Zdroj: | Current Diabetes Reports Okdahl, T & Brock, C 2021, ' Molecular Aspects in the Potential of Vitamins and Supplements for Treating Diabetic Neuropathy ', Current Diabetes Reports, vol. 21, no. 9, 31 . https://doi.org/10.1007/s11892-021-01397-1 |
| ISSN: | 1539-0829 1534-4827 |
| Popis: | Purpose of Review To discuss and provide evidence-based data on dietary supplements as part of treating diabetic neuropathy Recent Findings Few randomized controlled trials are available, but some have shown beneficial efficacy of various dietary supplements on objective primary endpoints including nerve conduction velocities and axon potentials as well as subjective patient-reported outcomes. Summary No medical cure for diabetic neuropathy exists, and prevention is therefore crucial. Tight glucose control slows the progression of nerve damage in diabetes, but an unmet clinical need for effective interventions is warranted. Consequently, a growing number of patients turn to dietary supplements proposed to possess neuroprotective properties. However, the postulated effects are often not evidence-based as they have not been tested scientifically. Taken together, this review will focus on dietary supplements investigated in clinical trials for their potential capabilities in targeting the molecular mechanisms involved in the underlying pathogenesis of diabetic neuropathy. |
| Databáze: | OpenAIRE |
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