Three dimensional approach to investigating biological effects along energetic ion beam pathways
| Autor: | Qu Ying, Shuli Man, Guangming Zhou, Jian Zhang, Weidong Cui, Zengquan Wei, Wenjian Li, Xinglin Li, Shuguang Sun, Jufang Wang, Genming Jin, Tianren Sun, Yi Chen, Shanying Wang, Fuping Lu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Multidisciplinary Materials science Ion beam Carbon chemistry Membrane filter Chlorella Saccharomyces cerevisiae Article Carbon Ion Computational physics 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Imaging Three-Dimensional Superoxides 030220 oncology & carcinogenesis Distribution model Heavy ion Heavy Ions Irradiation |
| Zdroj: | Scientific Reports |
| ISSN: | 2045-2322 |
| Popis: | Heavy ion beams have many exciting applications, including radiotherapy of deep-seated tumors and simulation tests of space irradiation for astronauts. These beams often use a feature that concentrates the energy deposition largely along the end of the energy pathway, leading to different distributions of biological effects along the axial direction. Currently, there is relatively little information regarding the radial directional difference of biological effects along the heavy ion paths. This study utilized a filter membrane that was quantatively applied with cells to demonstrate a 3D distribution model of irradiation on biological effects in living organisms. Some results have indicated that there is excitatory effect on the non-irradiated regions with energetic ions, which may give new insights into the distribution of biological effects along the paths of heavy ion beams with mid-high energy. |
| Databáze: | OpenAIRE |
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