Estimation of plasma insulin from plasma glucose
Autor: | J.R. Boston, C. Neatpisarnvanit |
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Rok vydání: | 2002 |
Předmět: |
Blood Glucose
medicine.medical_specialty medicine.medical_treatment Biomedical Engineering Models Biological Sensitivity and Specificity Dogs Control theory Internal medicine medicine Animals Humans Insulin Computer Simulation Patient treatment Mathematics Stochastic Processes Plasma glucose Glucose tolerance test medicine.diagnostic_test Noise (signal processing) Estimation theory Blood Glucose Self-Monitoring Models Cardiovascular Reproducibility of Results Estimator Signal Processing Computer-Assisted Glucose Tolerance Test Insulin kinetics Endocrinology Models Chemical Nonlinear Dynamics Intravenous Glucose Tolerance Test Plasma insulin Biological system |
Zdroj: | IEEE Transactions on Biomedical Engineering. 49:1253-1259 |
ISSN: | 0018-9294 |
Popis: | Two plasma insulin estimators are derived and evaluated in this paper. The estimators use continuously monitored plasma glucose, and they are based on a simple mathematical model of glucose-insulin metabolism. The first estimator (Estimator 1) was obtained from the glucose subsystem of the simplified model, which includes plasma glucose and interstitial insulin compartments. The second estimator (Estimator 2) was developed from the insulin kinetics subsystem of the simplified model. The performances of the estimators were compared using computer simulations and data from clinical intravenous glucose tolerance test procedures and from animal experiments. |
Databáze: | OpenAIRE |
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