Recuperación motora después de dos trasplantes de células mononucleares de la médula ósea, administrados en el espacio subaracnoideo, utilizando modelo de lesión aguda y grave de la médula espinal
| Autor: | Léder Leal Xavier, Gianina Terribele Venturin, Pamela Brambilla Bagatini, Elisa Lettnin Kaminski, Asdrubal Falavigna, Daniel Rodrigo Marinowic, Jaderson Costa DaCosta |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Bone marrow cells
lcsh:Diseases of the musculoskeletal system Células de la médula ósea Stem cells Punção lombar lcsh:RD701-811 Lesões da medula espinal lcsh:Orthopedic surgery Spinal cord injuries Lumbar puncture Orthopedics and Sports Medicine Surgery Neurology (clinical) Lesiones de la médula espinal Punción lumbar lcsh:RC925-935 Células-tronco Células da medula óssea |
| Zdroj: | Coluna/Columna, Vol 12, Iss 4, Pp 274-277 (2013) Coluna/Columna v.12 n.4 2013 Coluna/Columna Sociedade Brasileira de Coluna (SBCO) instacron:SBCO Coluna/Columna, Volume: 12, Issue: 4, Pages: 274-277, Published: DEC 2013 |
| Popis: | OBJECTIVE: We studied transplants of bone marrow mononuclear cells (BMMC) by lumbar puncture (LP) in a severe model of spinal cord injury (SCI) using clip compression. METHODS: BMMCs or saline solution were transplanted by LP 48 hours and 9 days post injury. Motor function was evaluated by BBB scale, histological analysis by Nissl technique and the verification of cell migration by PCR analysis. RESULTS: The BBB had significantly improved in rats treated with BMMCs by LP compared with controls (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|