Diagnostic error as a result of drug-laboratory test interactions
| Autor: | Wytze P. Oosterhuis, Heleen van der Sijs, Albert J de Graaf, Wilhelmine P.H.G. Verboeket-van de Venne, Holger K. de Wolf, Jasmijn A. van Balveren, Ron Kusters, Rein M.J. Hoedemakers, Lale Erdem-Eraslan, Rolf J Verheul, Ruben E A Musson, Annemarieke E. Loot, Martin P. Schuijt |
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| Přispěvatelé: | Clinical Chemistry, Pharmacy |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Decision support system Clinical laboratory test Clinical Biochemistry Medicine (miscellaneous) 030209 endocrinology & metabolism diagnostic error 030204 cardiovascular system & hematology 03 medical and health sciences Patient safety 0302 clinical medicine patient safety medicine Humans Drug Interactions Diagnostic Errors Intensive care medicine Health professionals Clinical Laboratory Techniques business.industry Health Policy Biochemistry (medical) Public Health Environmental and Occupational Health Decision Support Systems Clinical Test (assessment) Clinical Practice Laboratory test Harm clinical laboratory test drug-laboratory test interaction business (computerized) clinical decision support |
| Zdroj: | Diagnosis, 6(1), 69-71. De Gruyter |
| ISSN: | 2194-802X 2194-8011 2018-0098 |
| DOI: | 10.1515/dx-2018-0098 |
| Popis: | Background Knowledge of possible drug-laboratory test interactions (DLTIs) is important for the interpretation of laboratory test results. Test results may be affected by physiological or analytical drug effects. Failure to recognize these interactions may lead to misinterpretation of test results, a delayed or erroneous diagnosis or unnecessary extra tests or therapy, which may harm patients. Content Thousands of interactions have been reported in the literature, but are often fragmentarily described and some papers even reported contradictory findings. How can healthcare professionals become aware of all these possible interactions in their individual patients? DLTI decision support applications could be a good solution. In a literature search, only four relevant studies have been found on DLTI decision support applications in clinical practice. These studies show a potential benefit of automated DLTI messages to physicians for the interpretation of laboratory test results. All physicians reported that part of the DLTI messages were useful. In one study, 74% of physicians even sometimes refrained from further additional examination. Summary and outlook Unrecognized DLTIs potentially cause diagnostic errors in a large number of patients. Therefore, efforts to avoid these errors, for example with a DLTI decision support application, could tremendously improve patient outcome. |
| Databáze: | OpenAIRE |
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