Fast Method for Synthesis of Alkyl and Aryl-N-Methylnitrones
| Autor: | Hamdi Özkan, Serkan Yavuz, Yılmaz Yıldırır, Naki Çolak |
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| Přispěvatelé: | Hitit Üniversitesi, Fen Edebiyat Fakültesi, Kimya Bölümü |
| Rok vydání: | 2011 |
| Předmět: |
Time Factors
solid-phase synthesis Hydrochloride Proton Magnetic Resonance Spectroscopy Chemistry Organic Pharmaceutical Science 010402 general chemistry 01 natural sciences Article Analytical Chemistry Nitrone lcsh:QD241-441 Alicyclic compound chemistry.chemical_compound Solid-phase synthesis lcsh:Organic chemistry Drug Discovery Transition Temperature Organic chemistry Physical and Theoretical Chemistry Alkyl nitrone chemistry.chemical_classification 010405 organic chemistry Chemistry Aryl solventless Organic Chemistry grinding 0104 chemical sciences Grinding Solvent Chemistry (miscellaneous) Molecular Medicine Nitrogen Oxides |
| Zdroj: | Molecules; Volume 16; Issue 8; Pages: 6677-6683 Molecules, Vol 16, Iss 8, Pp 6677-6683 (2011) Molecules |
| ISSN: | 1420-3049 |
| DOI: | 10.3390/molecules16086677 |
| Popis: | A simple, fast, efficient and eco-friendly procedure was developed for the synthesis of alkyl and aryl-N-methylnitrones. The corresponding nitrones of aromatic aldehydes, aliphatic aldehydes and alicyclic carbonyl compounds were prepared from N-methylhydroxylamine hydrochloride and Na2CO3-Na2SO4 by simply grinding at room temperature without using solvent. |
| Databáze: | OpenAIRE |
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