Antioedematogenic activity, acetylcholinesterase inhibition and antimicrobial properties of Jacaranda oxyphylla
| Autor: | Jacqueline A. Takahashi, Danielle Ferreira Dias, Vinicius Viana Pereira, M. E. C. Moreira, M.H. dos Santos, Roqueline R. Silva |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Staphylococcus aureus
medicine.drug_class Phytochemicals Bignoniaceae Plant Science Biology 01 natural sciences Biochemistry Anti-inflammatory Analytical Chemistry Jacaranda Terpene Bacillus cereus Botany Escherichia coli medicine Edema Inflammation Traditional medicine Plant Extracts Terpenes 010405 organic chemistry Organic Chemistry biology.organism_classification Antimicrobial Terpenoid Anti-Bacterial Agents 0104 chemical sciences Plant Leaves 010404 medicinal & biomolecular chemistry Phytochemical Cholinesterase Inhibitors Medicine Traditional Antibacterial activity Brazil |
| Zdroj: | Natural Product Research. 30:1974-1979 |
| ISSN: | 1478-6427 1478-6419 |
| Popis: | Jacaranda oxyphylla Cham. (Bignoniaceae) is a shrub found in the Brazilian cerrado and used in folk medicine to treat microbial infections. The aim of this study was to carry out a phytochemical screening and evaluate antioedematogenic, antimicrobial and antiacetylcholinesterase properties of J. oxyphylla crude extracts. All extracts analysed showed presence of terpenoids, which are potentially active chemical substances. A high AChE inhibitory activity for hexane extract from leaves and for the extracts from twigs was found. Ethanol extract from leaves of J. oxyphylla showed activity against Gram-positive (Staphylococcus aureus and Bacillus cereus) and Gram-negative (Escherichia coli) bacteria. This extract was also effective in inhibiting the stages of inflammation evaluated. Biological investigation and phytochemical screening of J. oxyphylla extracts provided additional evidence of its traditional medicinal value. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|