Potentiation of Catechin Gallate-Mediated Sensitization of Staphylococcus aureus to Oxacillin by Nongalloylated Catechins
| Autor: | Paul D. Stapleton, Peter W. Taylor, Saroj Shah, Yukihiko Hara |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Staphylococcus aureus
Micrococcaceae medicine.drug_class Antibiotics Microbial Sensitivity Tests medicine.disease_cause complex mixtures Catechin Microbiology chemistry.chemical_compound medicine heterocyclic compounds Pharmacology (medical) Gallic acid Sensitization Oxacillin Antibacterial agent Pharmacology biology Chemistry food and beverages Drug Synergism Gallate biochemical phenomena metabolism and nutrition biology.organism_classification Infectious Diseases medicine.anatomical_structure Susceptibility sense organs |
| Zdroj: | Antimicrobial Agents and Chemotherapy. 50:752-755 |
| ISSN: | 1098-6596 0066-4804 |
| Popis: | (−)−Epicatechin gallate (ECg) and (−)−epigallocatechin gallate (EGCg) reduce oxacillin resistance in mecA -containing strains of Staphylococcus aureus . Their binding to staphylococcal cells is enhanced by the nongalloyl analogues (−)−epicatechin (EC) and (−)−epigallocatechin (EGC). EC and EGC significantly increased the capacity of ECg and EGCg to reduce levels of staphylococcal oxacillin resistance. |
| Databáze: | OpenAIRE |
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