Immunoassay of β2-microglobulin at oxide-coated heavily doped p-silicon electrodes
| Autor: | Päivi Kuosmanen, Kalle Salminen, Jarkko Uolevi Eskola, Heikki Peuravuori, Sakari Kulmala, Markus Håkansson |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Silicon
General Chemical Engineering Inorganic chemistry Oxide chemistry.chemical_element 02 engineering and technology 010402 general chemistry ta3111 01 natural sciences Analytical Chemistry chemistry.chemical_compound Electrochemistry medicine Immunoassays ta116 Hot electron-induced electrochemiluminescence Aqueous solution medicine.diagnostic_test Beta-2 microglobulin Doping technology industry and agriculture Bioaffinity assay Tb(III) chelates 021001 nanoscience & nanotechnology 0104 chemical sciences Electrogenerated chemiluminescence chemistry Immunoassay Electrode Silicon chip 0210 nano-technology |
| Zdroj: | JOURNAL OF ELECTROANALYTICAL CHEMISTRY. 769:11-15 |
| ISSN: | 1572-6657 |
| Popis: | An immunoassay was carried out on disposable oxide-coated silicon chip electrodes made of heavily doped p-type silicon, simply thermally oxidized in room air in a laboratory oven. The present electrode chips allow injection of hot electrons into aqueous electrolyte solutions and can be utilized in detecting electrochemiluminescent labels in fully aqueous solutions. This is demonstrated with an immunoassay of β2-microglobulin using an aromatic Tb(III) chelate as an electrochemiluminescent label. |
| Databáze: | OpenAIRE |
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