Influence of residual blood autotransfused from cardiopulmonary bypass circuit on clinical outcome after cardiac surgery
| Autor: | Edmundas Širvinskas, Jolanta Vaskelyte, Irena Marchertiene, Audrone Veikutiene, Tadas Lenkutis, Laima Raliene |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Male
medicine.medical_specialty Blood transfusion medicine.medical_treatment Postoperative Hemorrhage 030204 cardiovascular system & hematology Hematocrit law.invention Blood Transfusion Autologous 03 medical and health sciences 0302 clinical medicine law Blood product Internal medicine medicine Cardiopulmonary bypass Humans Radiology Nuclear Medicine and imaging Coronary Artery Bypass Adverse effect Aged Postoperative Care Advanced and Specialized Nursing Cardiopulmonary Bypass medicine.diagnostic_test business.industry General Medicine Middle Aged Intensive care unit Cardiac surgery Treatment Outcome 030228 respiratory system Anesthesia Cardiology Female Cardiology and Cardiovascular Medicine business Safety Research Autotransfusion |
| Zdroj: | Perfusion. 20:71-75 |
| ISSN: | 1477-111X 0267-6591 |
| DOI: | 10.1191/0267659105pf792oa |
| Popis: | Autotransfusion of the residual blood from the cardio-pulmonary bypass (CPB) circuit is considered to be one of the methods enabling reduction in the need for transfusion, the possible adverse effects of which are well known and documented. The aim of the study was to evaluate the effectiveness of the autologous autotrans-fusion of centrifuged red blood cells from the residual blood of the CPB circuit in patients following heart surgery. Three groups of patients who underwent heart surgery were examined. The first group (Group 1) consisted of 37 patients who received all of the residual blood in the bypass circuit after CPB (collected into sterile plastic bags) during the early postoperative period. The second group (Group 2) consisted of 45 patients who did not receive the residual blood following CPB. The third group (Group 3) consisted of 42 patients who underwent re-infusion of centrifuged red blood cells from the residual blood remaining in the CPB circuit during the early postoperative period. Hematocrit (Hct) values 12 hours after the operation were found to be higher in Group 3 compared with those of the first and the second groups (by 13.2% and 11.1%, respectively). Blood loss during the first 12 hours after the operation and during the time spent in the intensive care unit did not differ between the groups. The number of transfusions was significantly lower in Group 3 (28.57%) in comparison with that of Groups 1 and 2 (37.83% and 38.10%, respectively). The rate of infective complications in Group 3 was lower in comparison with both Group 1 and Group 2 (9.2% and 18.1%, respectively). The duration of in-hospital stay in Group 3 was 25.8% shorter than Group 1. We conclude that autotransfusion of centrifuged red blood cells processed from the residual blood of the CPB circuit after CPB was effective in increasing Hct values 12 hours postoperatively, reducing the need for donor blood product transfusions, the rate of infective complications and lenght of stay in hospital. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|