Advances in microRNA analysis
| Autor: | Iraklis K. Kyriakou, Panagiota M. Kalligosfyri, Despina P. Kalogianni, Theodore K. Christopoulos |
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| Rok vydání: | 2017 |
| Předmět: |
Mrna expression
Nanotechnology Biosensing Techniques 02 engineering and technology Computational biology Biology Spectrum Analysis Raman 01 natural sciences Biochemistry Chemistry Techniques Analytical Mass Spectrometry Analytical Chemistry Photometry microRNA Animals Humans Fluorometry 010401 analytical chemistry Nucleic Acid Hybridization Electrochemical Techniques Equipment Design 021001 nanoscience & nanotechnology Non-coding RNA 0104 chemical sciences Review article MicroRNAs Luminescent Measurements Quartz Crystal Microbalance Techniques 0210 nano-technology Nucleic Acid Amplification Techniques |
| Zdroj: | Analytical and Bioanalytical Chemistry. 410:695-713 |
| ISSN: | 1618-2650 1618-2642 |
| Popis: | MicroRNAs (miRNAs) are single-stranded noncoding RNA molecules that act as key regulators of mRNA expression and are emerging biomarkers for disease. Their small size (18-25 nt) presents challenges to molecular recognition, labeling, and signal generation. Recent research activity in this field has aimed at the development of methods for miRNA quantification that combine high detectability, broad dynamic range, practicality, multiplexity, and low cost for prospective applications in diagnostic laboratories. This review article covers the most recent advances in microRNA analysis. |
| Databáze: | OpenAIRE |
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