Processing affects beta-casomorphin peptide formation during simulated gastrointestinal digestion in both A1 and A2 milk
Autor: | J.M.L. Heck, Tim T. Lambers, Thom Huppertz, Sjef Broeren, Marjolijn C. E. Bragt |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: | |
Zdroj: | International Dairy Journal 121 (2021) International Dairy Journal, 121 |
ISSN: | 0958-6946 |
Popis: | Variation between bovine A1-or A2-type β-caseins are suggested to affect beta-casomorphin-7 (BCM-7) formation, which may affect health. Studies assessing BCM-7 formation often use raw milk, but processing of milk is known to affect digestion. Using in vitro digestion and stable-isotope assisted peptide quantification, we reveal that BCM-7 is formed under intestinal conditions from both A1-and A2-type milk. Moreover, formation of BCM-7 was affected by industrial relevant heating in both A1 and A2 milk. Further studies with a large number of single A1-and A2-type cows are needed to elaborate if amounts of BCM-7 formed are different between A1 and A2 milk. Both longer and shorter BCM peptide sequences that may display similar activities should be taking into account as a longer BCM-7 containing peptide (BCM-7 +2) could also be detected in A2 milk intestinal digesta. |
Databáze: | OpenAIRE |
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