Successful Treatment with Paclitaxel, Carboplatin, and Gemcitabine as Second-line Chemotherapy for Recurrent Urothelial Carcinoma of the Bladder with Glandular Differentiation After Radical Cystectomy: A Case Report
| Autor: | Hiroshi Kakizaki, Hiroki Fukuhara, Norihiko Tsuchiya, Yuya Kuboki, Hisashi Kaneko, Takuya Yamanobe, Masaki Ushijima |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Oncology
medicine.medical_specialty Urology medicine.medical_treatment 030232 urology & nephrology lcsh:RC870-923 Second-line chemotherapy Cystectomy 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine fluids and secretions Histological variant Internal medicine Medicine Cisplatin Chemotherapy Bladder cancer business.industry Combination chemotherapy medicine.disease lcsh:Diseases of the genitourinary system. Urology Carboplatin Gemcitabine chemistry Paclitaxel 030220 oncology & carcinogenesis embryonic structures Urothelial carcinoma business medicine.drug |
| Zdroj: | Urology Case Reports, Vol 15, Iss C, Pp 11-13 (2017) Urology Case Reports |
| ISSN: | 2214-4420 |
| Popis: | Urothelial carcinoma of the bladder (UCB) with glandular differentiation is a histological variant (HV) that is more likely to have positive extravesical tumors or nodes than those in pure UCB. Cisplatin-based neoadjuvant chemotherapy (NAC) prior to radical cystectomy (RC) is more effective for pure UCB; however, few reports are available on second-line chemotherapy for recurrence of UCB with HV. Here we report a 65-year-old Japanese male diagnosed with local recurrence UCB with HV after NAC + RC who safely achieved complete response with paclitaxel, carboplatin, and gemcitabine combination chemotherapy. |
| Databáze: | OpenAIRE |
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