Facilitation of delayed spontaneous alternation behavior in adult rats following early hydroxyzine treatment: Differential sensitivity in late infancy

Autor:	Ami Isseroff
Rok vydání:	1980
Předmět:	Male Pharmacology Hydroxyzine Aging Time Factors Behavior Animal Pharmacology toxicology Physiology Spontaneous alternation Rats Limbic system medicine.anatomical_structure Memory Anesthesia Male rats Facilitation medicine Animals Hydroxyzine hcl Psychology medicine.drug
Zdroj:	Psychopharmacology. 69:179-181
ISSN:	1432-2072 0033-3158
DOI:	10.1007/bf00427646
Popis:	When tested in adulthood, male rats that had been treated daily with 50 mg/kg hydroxyzine HCl SC at 10--29 or 23--29 days of age were significantly facilitated in performance of delayed spontaneous alternation relative to saline-injected rats. Treatment at 10--16 days of age did not produce significant facilitation in the delay task, nor were there any significant differences between groups in spontaneous alternation with no intertrial delay. The facilitative effect may be attributable to anomalies in areas, such as the limbic system, that continue to develop postnatally and mature in late infancy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de422842694ddd21b2603a768ab7c5f1 https://doi.org/10.1007/bf00427646 Zobrazit plný text záznamu Full text from SpringerLink