Oesophageal motor and sensitivity abnormalities in non-obstructive dysphagia
| Autor: | Nasser Gueddah, Jacques Fournet, Alain Rolachon, E. Papillon, Benoit Bohn, R. Bost, Bruno Bonaz |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
Male medicine.medical_specialty Manometry Distension Balloon Gastroenterology Catheterization Esophagus Internal medicine medicine Humans Ingestion Esophageal Motility Disorders Prospective Studies Hepatology Esophageal disease business.industry medicine.disease Dysphagia Deglutition medicine.anatomical_structure Sensitivity test Food Case-Control Studies Female Peristalsis Esophagogastric Junction medicine.symptom Abnormality Deglutition Disorders business |
| Zdroj: | European Journal of Gastroenterology & Hepatology. 14:271-277 |
| ISSN: | 0954-691X |
| DOI: | 10.1097/00042737-200203000-00011 |
| Popis: | To evaluate oesophageal sensitivity to balloon distension in patients with non-obstructive dysphagia (NOD), and to determine its relationship with the motility pattern in response to food ingestion.Twenty-one healthy volunteers and 19 consecutive patients complaining of NOD with normal standard manometry were included. An oesophageal sensitivity test was carried out before the manometry study with liquid and solid swallows.The median threshold to distension was 9 ml in control subjects and 5 ml in patients (P0.002). Dysphagia or odynophagia were reproduced in 15/19 (78.9%) patients during manometry with solid swallows only. The percentage of swallows with abnormal motility patterns was higher in patients than control subjects (P0.001). Compared with control values, sensitivity abnormality was defined by a distension threshold of6 ml. Motor abnormality was defined by19% of swallows occurring with one or more abnormal motor profiles. A total of 8/19 (42%) patients presented with the association of an abnormal sensitivity threshold and an abnormal motor pattern; 5/19 (26%) presented with isolated motor abnormalities; 4/19 (21%) patients presented with isolated abnormal sensitivity thresholds; and 2/19 (11%) patients presented without any abnormality.Manometry with solid swallows and oesophageal balloon distension are useful in characterizing NOD. |
| Databáze: | OpenAIRE |
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