Combined Use of Biologically Active Hemostatic and Granulated Sorbent in Endoscopic Cytoprotective Hemostasis in Patients with Bleeding Gastroduodenal Ulcers
| Autor: | Alexandr Zhdanov, Sergey Barannikov, Galina V. Polubkova, Darya Myachina, Ivan Moshurov, Evgeniy Ovsyannikov, Evgeniy Cherednikov, Yuri Maleev |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
platelet-rich auto-plasma Sorbent General Immunology and Microbiology business.industry General Neuroscience lcsh:R Combined use lcsh:Medicine hemostatic agent endoscopic hemostasis Gastroenterology General Biochemistry Genetics and Molecular Biology cytoprotective sorbents Internal medicine Hemostasis medicine bleeding gastroduodenal ulcers In patient business |
| Zdroj: | International Journal of Biomedicine, Vol 10, Iss 2, Pp 129-132 (2020) |
| ISSN: | 2158-0529 2158-0510 |
| DOI: | 10.21103/article10(2)_oa8 |
| Popis: | Background: The treatment of ulcerative gastroduodenal bleeding (GDB) remains one of the most acute problems in emergency surgery. The aim of our research was to improve the results of treatment of patients with bleeding gastroduodenal ulcers (GDUs) through the use of endoscopic pneumatic applications of platelet-rich auto-plasma (PRAP) and the cytoprotective sorbent Aseptisorb-A. Methods and Results: The study included 112 patients with bleeding GDUs. All patients were divided, by random sampling, into two equivalent groups: the main group (MG, n=57) and the comparison group (CG, n=55). In the treatment of MG patients, an individual approach was applied that used Aseptisorb-A and biologically active hemostatic agent PRAP in the complex endoscopic treatment of GDU complicated by bleeding. In CG, traditional methods of endoscopic hemostasis (EH) were used without PRAP and granular sorbents. After that, complex treatment of patients in the MG and CG did not differ. The relapse rate and operational activity was 3.5% in the MG and 10.9% in the CG (P=0.04); mortality rate was 1.75% in the MG and 5.45% in the CG; the duration of inpatient treatment in the MG and the CG was noted within 6.0(5.0;7.0) and 9.0(8.0;10.0) days, respectively (P |
| Databáze: | OpenAIRE |
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